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In conclusion, the wholesale classification of calcium carbonate is an important aspect of the calcium carbonate industry that helps categorize and differentiate the different grades of calcium carbonate based on their quality and intended use. Whether it is for pharmaceutical, food, industrial, or agricultural applications, there is a suitable grade of calcium carbonate available to meet the specific requirements of each industry. This classification system ensures that the right grade of calcium carbonate is used for the right application, ultimately leading to better quality products and improved performance.

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In a review published in 2022 in the journal Archives of Toxicologyresearchers found that the ingestion of E171 is a “a definite health risk for consumers and their progeny.” After reviewing dozens of in vivoex vivo and in vitro studies on the toxicity of E171, the researchers wrote that two facts must be noted: “First, reprotoxicity studies show that animals of both sexes are impacted by the toxicity of these nanoparticles, underlining the importance of conducting in vivo studies using both male and female animals. Second, human exposure begins in utero via maternal-fetal transfer and continues after birth by breastfeeding. Children are then chronically re-exposed due to their food preferences. To be relevant to the human in vivo situation, experimental studies should therefore consider nanoparticle exposure with respect to the age or life period of the studied population.”

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