At the present JECFA meeting, the committee considered additional toxicological studies relevant to the safety assessment of the chemical that investigated its toxicokinetics, acute toxicity, short-term toxicity, long-term toxicity and carcinogenicity, genotoxicity, and reproductive and developmental toxicity, as well as special studies addressing its short-term initiation/promotion potential for colon cancer. The experts acknowledged that a large number of toxicological studies have been conducted using test materials, including nanoparticles, having size distributions and physico-chemical properties not comparable to real-world uses of titanium dioxide as a food additive. The studies on non-representative materials were evaluated by JECFA, but the committee concluded that such studies are not relevant to the safety assessment of the additive.

The brands of lithopone of the normal class, that of chemical manufacture, are marketed under such names as Ponolith, Beckton White, Jersey Lily White, Oleum White, Zinc Sulphide White, all of these being of domestic manufacture, and their composition is of the 30 per cent. zinc sulphide type. The German manufacturers and exporters of lithopone make use of fancy names for their brands and here are a few examples of these and the composition of the pigment:-