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Additionally, the committee noted that the available data did not provide convincing evidence of genotoxicity for titanium dioxide as a food additive, but recognized the limitations in current methodologies with respect to the testing of poorly soluble particulate materials. Although there were uncertainties in the genotoxicity data, the experts took into account the fact that the additive was not carcinogenic in adequately conducted two-year studies in mice and rats at doses of up to 7,500 mg/kg BW per day for mice, and 2,500 mg/kg BW per day for rats, the highest doses tested. There was also no evidence of reproductive or developmental toxicity in studies in rats at doses up to 1,000 mg/kg BW per day, the highest doses tested.  

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lithopone prices supplier2025-08-15 00:12
2342

In conclusion, the use of food-safe titanium dioxide in manufacturing poses both promises and perils. While it is an effective and affordable whitening agent, there are concerns regarding its potential health risks when consumed in large quantities over a long period of time. To address these concerns, it is important for manufacturers to take steps to ensure the safe use of TiO2 in their products, and for regulatory agencies to establish stronger guidelines and regulations regarding its use.

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lithopone prices supplier2025-08-14 22:32
2202