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The National Cancer Institute tested TiO2 for possible carcinogenicity by the oral route of exposure by feeding rats and mice with TiO2 (size not specified) at doses 25,000 or 50,000 ppm TiO2 for 103 weeks. They concluded that TiO2 was not carcinogenic.Also, the study with rats fed diets containing up to 5 % TiO2 coated mica for 130 weeks showed no treatment-related carcinogenicity. Since the size and other TiO2 properties were not specified or determined, we cannot generalize this conclusion and we have to take into account other possible outcomes of this scenario in different exposure conditions (other size/crystalline structure of TiO2 etc.).

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To address this environmental challenge, Chinese companies have been investing in research and development to improve the efficiency of TiO2 production methods and reduce their carbon footprint. For instance, the adoption of advanced technologies like the sulfate process, which has lower emissions compared to the chloride process, is being encouraged. Additionally, there is a growing focus on utilizing renewable energy sources to power these manufacturing plants.

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In conclusion, titanium dioxide is an indispensable additive for plastic factories due to its multifaceted benefits. From protecting against UV damage to enhancing physical strength and improving aesthetic qualities, TiO2 plays a critical role in producing high-quality plastic products that meet the demands of modern industry and consumer expectations. As research continues to explore new applications and improvements in this field, the significance of titanium dioxide in plastic manufacturing is poised to grow even further.

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