The second quarter of 2022 saw mixed market sentiments for titanium dioxide prices. Due to demands, constrained supply and ineffective production capacity brought on by the stretched supply chain, labour shortage, and high energy prices, the production of the chemical increased in Q2 of 2022. Moreover, the US Federal Reserve's tight monetary policy and high interest rates worsened the domestic trade picture, which at quarter's conclusion supported titanium dioxide's unfavourable market views.

JECFA also evaluated estimates of dietary exposure to titanium dioxide, estimating the maximum 95^th percentile of exposure to be 10 mg/kg BW per day. Overall, considering the low oral absorption of titanium dioxide as a food additive, the committee reaffirmed the ADI “not specified” that was established at the 13^th meeting.