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In conclusion, the rutile type TiO2 stands out for its robust physical and chemical properties, which translate into a myriad of practical applications. From enhancing the performance of industrial coatings to aiding environmental clean-up efforts, rutile continues to be a cornerstone material in modern industry and science. As research progresses, it is likely that new uses for this remarkable substance will be discovered, further cementing its status as a versatile and indispensable material.

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In a small study published in the European Journal of Nutrition in 2020, researchers examined the effects of several food additives, including titanium dioxide, along with artificial sweeteners and cleaning products by testing the fecal samples of 13 people. Titanium dioxide was among the samples that “induced significant shifts in microbiome community structure.”  The growth of the bacterium species belonging to C. leptum, which has been shown to decrease in patients with inflammatory bowel disease, “significantly decreased in the presence of … titanium dioxide” among other additives and sweeteners tested.

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