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In conclusion, the market for titanium dioxide is evolving towards a greater emphasis on sustainability and value. Eco-friendly TiO2 suppliers who balance the best price with environmental responsibility and product quality are poised to lead the industry. As consumer awareness grows regarding the importance of sustainable materials, partnerships with such suppliers will become increasingly vital for businesses looking to maintain a competitive edge and a clean conscience.

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One of the key findings of the report is the increasing demand for titanium dioxide in the paints and coatings industry. With the growth of the construction sector, there is a rising need for high-quality paints and coatings, which is driving the demand for titanium dioxide as a key ingredient. Key manufacturers in the market are focusing on developing innovative products to cater to the specific requirements of their customers in the paints and coatings industry.

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Over the last several years, nanoparticles have come under scrutiny for adverse health effects. Nanoparticles are ultrafine particles between 1 to 100 nanometers in diameter. (To put this in perspective, the average human hair is around 80,000 nanometers thick.) Because of their size, which can be engineered and manipulated at the atomic or molecular level, nanoparticles exhibit unique physical, chemical, and biological properties. Titanium dioxide is one of the most commonly produced nanoparticles in the world.

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The first study addressing the experimental convergence between in vitro spiking neurons and spiking memristors was attempted in 2013 (Gater et al., 2013). A few years later, Gupta et al. (2016) used TiO2 memristors to compress information on biological neural spikes recorded in real time. In these in vitro studies electrical communication with biological cells, as well as their incubation, was investigated using multielectrode arrays (MEAs). Alternatively, TiO2 thin films may serve as an interface material in various biohybrid devices. The bio- and neurocompatibility of a TiO2 film has been demonstrated in terms of its excellent adsorption of polylysine and primary neuronal cultures, high vitality, and electrophysiological activity (Roncador et al., 2017). Thus, TiO2 can be implemented as a nanobiointerface coating and integrated with memristive electronics either as a planar configuration of memristors and electrodes (Illarionov et al., 2019) or as a functionalization of MEAs to provide good cell adhesion and signal transmission. The known examples are electrolyte/TiO2/Si(p-type) capacitors (Schoen and Fromherz, 2008) or capacitive TiO2/Al electrodes (Serb et al., 2020). As a demonstration of the state of the art, an attempt at memristive interlinking between the brain and brain-inspired devices has been recently reported (Serb et al., 2020). The long-term potentiation and depression of TiO2-based memristive synapses have been demonstrated in relation to the neuronal firing rates of biologically active cells. Further advancement in this area is expected to result in scalable on-node processors for brain–chip interfaces (Gupta et al., 2016). As of 2017, the state of the art of, and perspectives on, coupling between the resistive switching devices and biological neurons have been reviewed (Chiolerio et al., 2017).

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