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Zhu et al. were the first to provide evidence that TiO2 NPs (21 nm) can transfer from daphnia to zebrafish by dietary exposure. Hence, dietary intake could be a major route of exposure to NPs for high trophic level aquatic organisms. Ecological research should therefore focus, not only on the concentration of NPs in the environment, but also on its bioconcentration, bioaccumulation and biomagnification. In addition it has been shown that TiO2 NPs can increase accumulation of other environmental toxicants: enhanced accumulation of cadmium (Cd) and arsenic (As) was found in carp in the presence of TiO2 NPs. The strong adsorption capacity for Cd and As was explained by the large specific surface area and strong electrostatic attraction of TiO2 NPs that contribute to facilitated transport into different organs.

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Firstly, TiO2 is commonly used as a white pigment in plastic products. Its high refractive index and ability to scatter light across the visible spectrum provide excellent opacity and brightness to plastic materials. This makes it an essential component in producing white or light-colored plastics, such as packaging materials, household items, and toys. The addition of TiO2 not only enhances the aesthetic appeal of these products but also improves their overall quality by increasing their durability and resistance to UV radiation.

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