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In its 2016 opinion, the ANS Panel recommended new studies be carried out to fill the gaps on possible effects on the reproductive system, which could enable them to set an Acceptable Daily Intake (ADI ). Uncertainty around the characterisation of the material used as the food additive (E 171) was also highlighted, in particular with respect to particle size and particle size distribution of titanium dioxide used as E 171.   

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Lithopone was discovered in the 1870s by DuPont. It was manufactured by Krebs Pigments and Chemical Company and other companies.[2] The material came in different seals, which varied in the content of zinc sulfide. Gold seal and Bronze seals contain 40-50% zinc sulfide, offering more hiding power and strength.[3] Although its popularity peaked around 1920, approximately 223,352 tons were produced in 1990. It is mainly used in paints, putty, and in plastics.[1]

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Overall, choosing the right suppliers for brilliant blue FCF and titanium dioxide is essential for manufacturers in the food and beverage industry. By working with reputable suppliers that prioritize quality, reliability, and cost-effectiveness, manufacturers can ensure the safety and quality of their products while meeting regulatory requirements and consumer expectations. With the help of reliable suppliers, manufacturers can continue to produce high-quality food and beverage products that meet the ever-changing demands of the market.

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