titanium oxide tio2 manufacturer

The major restraint to the global Lithopone market is the availability of numerous white pigment substitutes. It can be replaced by other inorganic white pigments such as Titanium Dioxide (TiO2) and Sachtolith. Among these substitutes, the introduction of TiO2 has reduced the commercial importance of Lithopone white pigment. Compared to other white pigments, TiO2 has high brightness and refractive index, which results in lower pigment loading. 

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One common method to determine sulfate as TiO2 involves gravimetric analysis. In this technique, a sample containing sulfate is treated with barium chloride, resulting in the precipitation of barium sulfate. The precipitate is then filtered, dried, and weighed. The weight of the barium sulfate precipitate correlates directly with the amount of sulfate originally present in the sample. To express this as TiO2, a conversion factor based on stoichiometry is applied. This method, while straightforward, can be time-consuming and subject to errors in filtration and drying.

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Mexican researchers sought to evaluate the effects of E171 across a span of conditions in mice, including its influence on behavior, along with the effects on the colon and liver. The research, published in 2020 in the journal Food and Chemical Toxicology, showed that E171 promoted anxiety and induced adenomas, or noncancerous tumors, in the colon. They also found that E171 heightened goblet cells hypertrophy and hyperplasia, which is typically seen in asthma patients and triggered by smoking or external pollutants and toxins. They also noted mucins overexpression in the mice, which can be linked to cancer cell formation. 

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