French researchers studied how and where E171 nanoparticles enter the bloodstream, first studying the route through pigs and then in vitro with human buccal cells, for a 2023 study published in the journal Nanotoxicology. The research showed that the nanoparticles absorbed quickly through the mouth and then into the bloodstream, before damaging DNA and hindering cell regeneration.
Still, in 2016 Skittles publicly declared it would get rid of the chemical compound in its products, according to a press release at the time from the Center for Food Safety, which called the substance harmful and potentially poisonous. But the ingredient remains, according to the lawsuit, which alleges the candy company is misleading consumers by not having eliminated titanium dioxide.
Pendant longtemps on a reproché au lithopone sa mauvaise tenue à l'extérieur, due à la dégradation photolytique du sulfure de zinc et/ou à la présence de traces de chlore, provoquant un noircissement du revêtement. Même si la recherche a permis d'éradiquer en grande partie ce problème, on réserve son emploi dans les peintures intérieures pour les raisons suivantes :
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