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Prof Maged Younes, Chair of EFSA’s expert Panel on Food Additives and Flavourings (FAF), said: “Taking into account all available scientific studies and data, the Panel concluded that titanium dioxide can no longer be considered safe as a food additive . A critical element in reaching this conclusion is that we could not exclude genotoxicity concerns after consumption of titanium dioxide particles. After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body”. 

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One of the most significant impacts of TIO2 in factories is its role in photocatalysis. This process involves the acceleration of photoreaction in the presence of light and a catalyst—in this case, TIO2. By harnessing the power of sunlight or artificial UV light, TIO2 can break down organic pollutants into substances, playing a crucial role in environmental remediation efforts within industrial settings. This not only helps factories minimize their environmental footprint but also reduces the costs associated with waste treatment and disposal.

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On the other hand, the U.S. Food and Drug Administration (FDA) in their Final Administrative Order on Sunscreen Drug Products posted in September 2021 still accepts titanium dioxide up to 25% in the list of Generally Recognized As Safe and Effective (GRASE) in the main document, without further clarification on what kind or size of particles [9]. However, on page 24 (Sunscreen containing nanomaterials) FDA clearly “distinguish nanomaterials from other forms of these ingredients'' (zinc oxide and titanium dioxide) and ask for comments on “any particular nanomaterials that you believe should not be permitted for use in OTC sunscreen products”. To the best of our knowledge, this Agency did not ban the use of nanoparticulate titanium dioxide in any form, even though it is mentioned on page 34 that the anatase form is the more photoactive one, due to the lack of evidence with real sunscreens OTC (over the counter) in vivo. Moreover, other regulations in Latin America (MERCOSUR agreement, 2006) do not state clearly their position on the use of nanoparticulate TiO2NPs [10].

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Anatase, known for its excellent photocatalytic activity, is primarily used in the production of advanced materials and environmental protection products. Its unique ability to break down pollutants under sunlight makes it an ideal choice for air purification and self-cleaning surfaces. On the other hand, Rutile, with its superior opacity and durability, is more commonly used in the coatings, plastics, and paper industries, providing a white pigment and UV protection.

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In conclusion, the quality of Chinese lithopone stands as a testament to the nation's unwavering commitment to excellence and sustainability. Through continuous innovation, responsible sourcing, and adherence to stringent quality controls, China has positioned itself as a trusted supplier of this essential industrial pigment. As the world increasingly seeks reliable partners for its industrial needs, China's lithopone industry serves as a shining example of how dedication to quality can lead to global success.

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