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In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2. With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”
Research has shown that, when ingested as a food additive, titanium dioxide and its nanoparticles can impact, alter, and/or damage important protective bacteria in the gut, along with the metabolic pathways of gut bacteria.
Titanium Dioxide (TiO2) is an essential component in the coatings industry, playing a pivotal role in enhancing the performance and aesthetics of various coating products. In coatings factories worldwide, TiO2 is a critical raw material due to its unique properties that make it indispensable.
Furthermore, the use of R960 in TiO2 manufacturing also leads to environmental benefits. The catalyst systems that incorporate R960 generate significantly less waste and emissions compared to traditional methods, reducing the environmental footprint of TiO2 production.
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Titanium Dioxide DongFang R5566 Tio2 Powder
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Titanium Dioxide DongFang R5566 Tio2 Powder
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