This information from Lexicomp^® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.

Methyl cellulose (MC) and HPMC (hydroxypropyl methyl cellulose) are two types of cellulose-based polymers. Both are white powders used in a variety of industries, including food, pharmaceuticals, cosmetics, and construction. But what is the difference between methyl cellulose and HPMC?

Toxicological studies:

Hydroxypropyl Methylcellulose (HPMC) plays a crucial role in pharmaceutical formulations due to its diverse range of benefits. One of its primary uses is as a key component in controlled-release drug delivery systems. HPMC’s ability to modify drug release rates enables pharmaceutical companies to develop medications that provide sustained therapeutic effects, leading to improved patient compliance and reduced dosing frequency. Moreover, HPMC is utilized as a binder in tablet formulations, contributing to the mechanical strength and disintegration properties of tablets, thereby ensuring consistent drug release and bioavailability. Its biocompatibility and inert nature make it suitable for a wide range of drug formulations, including oral, topical, and ophthalmic products, underscoring its versatility in pharmaceutical applications.

Methyl cellulose and HPMC are both cellulose-based polymers, meaning they are nearly identical in chemical composition and structure. The main difference between the two is that HPMC has been modified with hydroxpropyl groups. HPMC is more water soluble and is therefore used in more industries than methyl cellulose. Methyl cellulose is more commonly used in food and cosmetics, while HPMC is more commonly used in pharmaceuticals and construction. In terms of application, however, there is very little difference between methyl cellulose and HPMC.

HPMC is made from natural cellulose and the appropriate removal of microbial impurities is a major manufacturing challenge.