Edelweiss, 14.5 per cent zinc sulphide, 84 per cent barium sulphate, 1.5 per cent carbonate of lime.
This classification was given, as some animal studies found that inhaling titanium dioxide dust might cause the development of lung tumors. However, IARC concluded that food products containing this additive do not pose this risk (11).
Recent analyses of food-grade TiO2 samples have found that a significant portion of particles may be within the nanoscale. These particles (also known as nanoparticles) range in size from 1 to 100 nm, where 1 nm equals 1 billionth of a metre (the width of a typical human hair is 80,000 to 100,000 nm).
TiO2 is also used in oral pharmaceutical formulations, and the Pharmaceutical Excipients handbook considers nano-sized TiO2 a non-irritant and non-toxic excipient. Despite the fact that TiO2 submicron- and nano-sized particles are widely used as food and pharmaceutical additives, information on their toxicity and distribution upon oral exposure is very limited.
Lithopone 30% is the perfect solution for partial substitution of TiO2 in fillers due to its very soft nature and hardly any shrinkage properties.
When E171 isn’t combined with other ingredients and administered in water, some studies suggest that under these artificial conditions, E171 may be processed differently in the body resulting in some biological changes in experimental animals that are poorly understood.