Lithopone, a white pigment composed of a mixture of zinc sulfide and barium sulfate, has become an indispensable ingredient in the paint industry. Its unique properties, including excellent opacity, high brightness, and resistance to weathering, make it highly valued among paint manufacturers. As the demand for sustainable and efficient paint products grows, the role of lithopone and its suppliers has become more critical than ever.

What titanium dioxide is really emblematic of ... is the failure of FDA to look back at these old decisions and ask whether its decisions that were made in this case ... 56 years ago (in the 1966 approval) still hold up, he said.

It's hard to determine the total amount of food products that have titanium dioxide because federal regulations don't require all producers to list its use on ingredient labels, but the list of foods containing the substance certainly doesn't end with Skittles.

Furthermore, lithopone is a versatile pigment that can be easily mixed with other coloring agents to create custom shades and finishes. This flexibility allows leather suppliers to meet the diverse needs of their customers and produce a wide range of leather products in different colors and styles. Whether it's a classic black leather jacket or a trendy pastel-colored purse, lithopone can be tailored to suit any design requirements.

Testing samples were made mixing 100 uL of TiO₂NPs suspensions (0.2 mg/mL and 0.02 mg/mL) and vitamins@P25TiO₂NPs (0.2 mg/mL and 0.02 mg/mL) with 100 μL ATCC 29,213 methicillin-sensitive Staphylococcus aureus (MSSA) (10⁷ in PBS, pH 7). Controls were made replacing nanoparticles with the same volume of PBS. The concentrations of nanoparticle suspensions were chosen based on the FDA approved maximal and the minimal amount usually found in sunscreens, which are 20% and 2% (this is equivalent to 0.2 mg/mL and 0.02 mg/mL for nanoparticles suspensions). The cream concentration, on the other hand, was an intermediate value of 10%.

A few non-dietary studies have reported adverse effects in the gastrointestinal tract of laboratory animals given food-grade TiO₂. However, these same effects were not seen when the same or higher doses of food-grade TiO₂ were administered in the animals' diet. Dietary studies best reflect how humans are exposed to TiO₂ from food. Thus, the Food Directorate placed the most emphasis on the results of these studies in the state of the science report.