R-895 is a paint grade titanium dioxide pigment produced by the chlorination process. Recommended for use in a variety of coating applications.

A few non-dietary studies have reported adverse effects in the gastrointestinal tract of laboratory animals given food-grade TiO₂. However, these same effects were not seen when the same or higher doses of food-grade TiO₂ were administered in the animals' diet. Dietary studies best reflect how humans are exposed to TiO₂ from food. Thus, the Food Directorate placed the most emphasis on the results of these studies in the state of the science report.

It's also worth noting that even prior to the EU decision, France had already outlawed titanium dioxide in food back in January 2020.

The trend in the production of NPs is likely to lead to increasing amounts of nano-powders in the air, water and soil, which will consequently affect living organisms. Labielle et al. demonstrated that 25 % of Al(OH)₃-coated TiO₂ particles from sunscreens are dispersed as a stable colloid and become available to microorganisms and filter-feeders, while the remaining 75 % are probably incorporated into geogenic sediments, where they could become available to benthic fauna. Solar UV iradiation may penetrate as far as 20 m in the water column  and therefore photo-activate the dispersed particles, which may have an adverse effect on various aquatic organisms.

Health advocates urge US regulators to ban common food coloring additive, by Tom Perkins, The Guardian, June 2, 2023

The California plaintiff is apparently not the only one concerned about titanium dioxide. The European Union recently banned its use citing concerns about serious health consequences.

The lack of clear regulations and controls explains that P25TiO₂NPs are still found in many of the commercialized sunscreens in the market. Some of them are coated to reduce the photoactivity of the anatase form, which is known to be responsible for tissue damage, but not enough studies were made on these coated forms. The anatase photoactivity could trigger the production of reactive oxygen species (ROS) generation, as it was stated before. The ROS are chemically reactive species containing oxygen, such as peroxides, superoxide, hydroxyl radical, and singlet oxygen. They are regularly produced in the biological milieu and counterbalanced by physiological antioxidant defense mechanisms. However, an abrupt increase of ROS may result in non-reversible damage to the skin cells. The effects of coated and uncoated P25TiO₂NPs need therefore to be studied, and articles on this topic present different conclusions. [11], [12], [13] Recent literature on this topic found that TiO₂NPs inhalation provokes serious genotoxicity and DNA damage [14], [15], [16], [17]. On the other hand, some studies in rats have reported no significant harm to genetic material [18], [19], [20], [21], [22].

Package:
25KG/50KG Woven bag with inner, or 1000kg big woven plastic bag.



Company Information
     Loman Chemical Group (include Shanghai Loman Chemical Co Ltd; Wuhu Loman Chemical Co Ltd and Wuhu Loman Titanium Industial Co Ltd.)is one of the main titanium dioxide manufacturers in china, producing various high quality Anatase and Rutile titanium dioxide. Loman brand products, has being widely used in paper, paint, plastic, ink, coating, rubber, cosmetic, food, fiber, etc.
      In order to meet different requirements of various customers, we actively expand producing other pigments, include Lithopone, Barium sulfate and Silica. Annual production volume of anatase and rutile grade titanium dioxide have reached 100,000 tons, lithopone 30.000 tons, barium sulfate 50.000 tons and precipitated silica 8.000 tons. The Loman brand is one of the famous brands in China, having great popularity both at home and abroad. Our products have been widely used in European, North America and Southeast Asia. 

Our advantages:
1)With the most professional manufacturers,High quality and high safety product

2)Professional consulting services are availabe for you at antyime

3)Have a favorable price ,reliable quality

4)Complete products meet your purchasing need

History

A study published in the Journal of Agricultural and Food Chemistry in 2019 sought to examine the effects of titanium dioxide on intestinal inflammation. Researchers did this by feeding rats titanium dioxide nanoparticles and found that, after the course of two to three months, the animals had lower body weights and induced intestinal inflammation. The researchers also found the nanoparticles altered gut microbiota composition and aggravated chronic colitis. The rats also experienced reduced populations of CD4+T cells (which are cells that help organize immune responses by prompting other immune cells to fight infection), regulatory T cells, and white blood cells in mesenteric lymph nodes. The researchers wrote: “Dietary TiO2 nanoparticles could interfere with the balance of the immune system and dynamic of gut microbiome, which may result in low-grade intestinal inflammation and aggravated immunological response to external stimulus, thus introducing potential health risk.”

In 2021, the European Food Safety Authority concluded that titanium dioxide is no longer safe in foods due to the same concerns over nanoparticles. As a result, titanium dioxide is now banned as a food additive in the EU. Although studies have shown that the absorption of ingested titanium dioxide is low, evidence suggests that titanium dioxide nanoparticles can accumulate in the body over time. Health Canada deemed it safe in 2022 but noted concerns. Unlike their European counterparts, Canadian officials did not consider studies performed with titanium dioxide nanoparticles alone. 

Furthermore, this packaging has been shown to have both antibacterial and photocatalytic activity, the latter of which reduces ultraviolet (UV) exposure (5Trusted Source, 6).

④ Ink industry: titanium dioxide is also an indispensable white pigment in advanced ink. The ink containing titanium dioxide is durable and does not change color, has good surface wettability and is easy to disperse. The titanium dioxide used in the ink industry includes rutile and anatase.

Lithopone B311

Skin-penetration studies