Second, the present invention provides a large-scale industrial production process with low production cost, high efficiency, energy saving, and stable product quality with an annual production capacity of several hundred thousand tons. Selective leaching of zinc by ammonia method, combined with ammonium persulfate iron removal, vulcanization method and zinc powder replacement method to remove heavy metal elements such as nickel, copper, lead, cadmium and arsenic, and metathesis reaction to obtain nZnS-B a S0 4 crystal filter cake. The nano-Lide powder product is obtained by directly drying and pulverizing without high-temperature calcination. The resulting product is of good quality and industrially operable.