titanium dioxide uses in medicine manufacturer

TiO2 NPs appeared to be more toxic to nematode Caenorhabditis elegans than submicron-sized TiO2.  At a concentration of 1 mg/l, 7 nm particles affected its fertility and survival rate and were more toxic than 20 nm anatase particles. Similarly, Hu et al. showed that rutile particles (10–20 nm), at concentrations above 1 g/kg soil, can be bio-accumulated in earthworms, where they induce oxidative stress, inhibit the activity of cellulase and induce DNA and mitochondrial damage.

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In addition to supplier evaluation and negotiation, BA311 also covers other critical aspects of supplier management, such as risk management, performance monitoring, and continuous improvement. The guide provides practical guidance on how to identify and mitigate potential risks associated with supplier relationships, how to measure supplier performance over time, and how to engage suppliers in continuous improvement efforts.

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