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In 2019, EFSA published a statement on the review of the risk related to the exposure to food additive titanium dioxide (E171) performed by the French Agency for Food, Environment and Occupational Health Safety (ANSES). In its statement, EFSA highlighted that the ANSES opinion reiterated the uncertainties and data gaps previously identified by EFSA and did not present findings that invalidated the Authority’s previous conclusions on the safety of titanium dioxide.

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In a study published in 2022 in the journal Particle and Fibre Technologyresearchers examined the impact of maternal exposure to titanium dioxide nanoparticles in newborn offspring mice. They found that “a chronic exposure to TiO2 NPs during pregnancy alters the respiratory activity of offspring, characterized by an abnormally elevated rate of breathing.” Breathing was also shown to be “significantly and abnormally accelerated,” and the ability for neural circuitry to effectively adjust breathing rates was impaired. The researchers concluded: “Our findings thus demonstrate that a maternal exposure to TiO2 NPs during pregnancy affects the normal development and operation of the respiratory centers in progeny.”

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In conclusion, the wholesale TiO2 market is a dynamic and competitive sector in the global chemical industry, driven by factors such as increasing demand for TiO2 in end-use industries, the shift towards sustainable production methods, and the demand for high-performance TiO2 grades. Manufacturers in the wholesale TiO2 market need to stay abreast of these trends and challenges to remain competitive and meet the evolving needs of their customers.

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