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The primary use of lithopone is in the paint industry, where it is utilized as a pigment to provide opacity and brightness to paint formulations. It is ideal for both interior and exterior paints due to its durability and lightfastness. Additionally, lithopone is also employed in the production of rubber products, where it helps improve the tensile strength and aging resistance of rubber compounds.
In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2. With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”
Titanium dioxide, often abbreviated as TiO2, is a white pigment widely used in the production of paints, plastics, paper, and other products. It's also utilized in photocatalytic applications due to its semiconducting properties. Titanium dioxide coatings are particularly valued for their ability to reflect ultraviolet light, making them useful in sunscreens and cosmetics, as well as in architectural materials where UV protection is needed.
What are the key regulatory procedures and requirements for setting up a lithopone manufacturing plant?
