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TiO2 pigment factories adhere to strict quality control measures to ensure that the pigment produced meets the required specifications and standards. The pigment undergoes rigorous testing at every stage of production to ensure its purity, color consistency, and other physical properties. This ensures that the TiO2 pigment produced by these factories is of the highest quality and suitable for various applications This ensures that the TiO2 pigment produced by these factories is of the highest quality and suitable for various applications This ensures that the TiO2 pigment produced by these factories is of the highest quality and suitable for various applications This ensures that the TiO2 pigment produced by these factories is of the highest quality and suitable for various applicationsti02 pigment factories.

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In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”

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