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In a small study published in the European Journal of Nutrition in 2020, researchers examined the effects of several food additives, including titanium dioxide, along with artificial sweeteners and cleaning products by testing the fecal samples of 13 people. Titanium dioxide was among the samples that “induced significant shifts in microbiome community structure.”  The growth of the bacterium species belonging to C. leptum, which has been shown to decrease in patients with inflammatory bowel disease, “significantly decreased in the presence of … titanium dioxide” among other additives and sweeteners tested.

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Leading titanium dioxide manufacturers have started to explore alternative synthesis routes that minimize waste and reduce energy consumption. For instance, some have turned to the sol-gel process, which allows for the production of nanoparticles at lower temperatures with better control over the particle size distribution. Others are looking into recycling waste streams from the manufacturing process to recover titanium compounds, thus closing the loop on material use Others are looking into recycling waste streams from the manufacturing process to recover titanium compounds, thus closing the loop on material use Others are looking into recycling waste streams from the manufacturing process to recover titanium compounds, thus closing the loop on material use Others are looking into recycling waste streams from the manufacturing process to recover titanium compounds, thus closing the loop on material usetitanium dioxid manufacturer.

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