china billions tio2

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No acute effects of nano-sized TiO2 were observed in Danio rerio (zebrafish) embryos. Exposure of rainbow trout to TiO2 NPs triggered lipid peroxidation, influence on the respiratory tract, disturbance in the metabolism of Cu and Zn, induction of intestinal erosion  and accumulation in kidney tissue. Linhua et al. exposed juvenile carp to 100 and 200 mg/ml of particles and TiO2 observed no mortality. However, the fish suffered from oxidative stress and pathological changes in gill and liver. In the infaunal species Arenicola marina, exposure to TiO2 NPs in sediment caused sub-lethal effects including decrease in casting rate and increase in cellular and DNA damage. Aggregated particles were visible in the lumen of the gut, but no uptake through the gut or the skin was observed.

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The production process of titanium dioxide involves several stages, starting with the extraction of raw materials from mineral ores such as ilmenite, rutile, and anatase. These ores are then processed through various methods, including the sulfate and chloride processes, to produce high-purity titanium dioxide powder. The sulfate process involves treating the ore with sulfuric acid to extract titanium dioxide, while the chloride process uses chlorine gas to produce a purer form of the pigment.

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