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However, it’s also important to note that such adverse effects depend heavily on the form of the titanium dioxide. It can come down to characteristics like “particle shape, purity, surface charge, solubility, agglomeration rate, photo-activation, etc.”
It's hard to determine the total amount of food products that have titanium dioxide because federal regulations don't require all producers to list its use on ingredient labels, but the list of foods containing the substance certainly doesn't end with Skittles.
Because of their small size, nanoparticles may have unique physical and chemical properties. These properties may cause them to interact with living systems differently than larger materials with the same chemical composition (also known as bulk materials).