R-5568:

In conclusion, the role of lithopone in the paint industry cannot be overstated. Its unique properties make it a vital component in producing high-quality paints and coatings. As the market continues to evolve with a focus on sustainability and performance, lithopone suppliers are stepping up to meet these challenges through innovative production techniques and a commitment to quality. By partnering with these suppliers, paint manufacturers can ensure they are equipped with the best possible materials to create products that not only meet consumer expectations but also contribute to a more sustainable future.

At the present JECFA meeting, the committee considered additional toxicological studies relevant to the safety assessment of the chemical that investigated its toxicokinetics, acute toxicity, short-term toxicity, long-term toxicity and carcinogenicity, genotoxicity, and reproductive and developmental toxicity, as well as special studies addressing its short-term initiation/promotion potential for colon cancer. The experts acknowledged that a large number of toxicological studies have been conducted using test materials, including nanoparticles, having size distributions and physico-chemical properties not comparable to real-world uses of titanium dioxide as a food additive. The studies on non-representative materials were evaluated by JECFA, but the committee concluded that such studies are not relevant to the safety assessment of the additive.

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