One of the key responsibilities of titanium dioxide manufacturers is to produce high-quality products that meet the stringent requirements of their customers. This involves carefully sourcing raw materials, employing efficient production processes, and conducting rigorous quality control measures to ensure that the final product meets the necessary specifications.

The FDA is reviewing the safety of titanium dioxide in response to an April petition from EWG and other environmental and public health groups. This is the FDA’s first comprehensive review of titanium dioxide since 1973.

2. Particle Size The application often dictates the required particle size. Suppliers typically offer various grades of barium sulphate, categorized by their particle size distribution. For example, finer particle sizes are often favored in cosmetic applications, while coarser grades may be used in construction materials.

Mexican researchers sought to evaluate the effects of E171 across a span of conditions in mice, including its influence on behavior, along with the effects on the colon and liver. The research, published in 2020 in the journal Food and Chemical Toxicology, showed that E171 promoted anxiety and induced adenomas, or noncancerous tumors, in the colon. They also found that E171 heightened goblet cells hypertrophy and hyperplasia, which is typically seen in asthma patients and triggered by smoking or external pollutants and toxins. They also noted mucins overexpression in the mice, which can be linked to cancer cell formation.