Animal studies show exposure to titanium dioxide is linked to immunotoxicity, inflammation and neurotoxicity. 

The pricing of lithopone pigments can fluctuate based on several factors, including raw material costs, production processes, and market demand. Typically, wholesale prices reflect the bulk purchasing power, enabling businesses to acquire these materials at a lower cost per unit. Over the years, the market has seen fluctuations in prices due to changes in the supply chain and global economic conditions. It is crucial for buyers to stay informed about these trends to budget effectively and maintain profitability.