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Additionally, the committee noted that the available data did not provide convincing evidence of genotoxicity for titanium dioxide as a food additive, but recognized the limitations in current methodologies with respect to the testing of poorly soluble particulate materials. Although there were uncertainties in the genotoxicity data, the experts took into account the fact that the additive was not carcinogenic in adequately conducted two-year studies in mice and rats at doses of up to 7,500 mg/kg BW per day for mice, and 2,500 mg/kg BW per day for rats, the highest doses tested. There was also no evidence of reproductive or developmental toxicity in studies in rats at doses up to 1,000 mg/kg BW per day, the highest doses tested.  

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In interior applications, titanium dioxide's non-toxic nature makes it suitable for use in areas with high human contact, such as homes and officestitanium dioxide for interior and exterior wall paint material factory. It does not release harmful substances into the air, ensuring indoor environments remain safe and healthy. Furthermore, its excellent hiding power allows for effective coverage even in small spaces where natural light may be limited, creating a consistent and aesthetically pleasing finish.

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