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China has emerged as a pivotal player in the global titanium dioxide industry, with its importers playing a crucial role in shaping the dynamics of this sector. Titanium dioxide, also known as TiO2, is a white pigment widely used in various applications such as paints, plastics, paper, and cosmetics. The country's growing demand for this versatile compound has led to an increase in import activities, making Chinese importers a vital link between domestic consumers and international producers.

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In its 2016 opinion, the ANS Panel recommended new studies be carried out to fill the gaps on possible effects on the reproductive system, which could enable them to set an Acceptable Daily Intake (ADI ). Uncertainty around the characterisation of the material used as the food additive (E 171) was also highlighted, in particular with respect to particle size and particle size distribution of titanium dioxide used as E 171.   

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