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In a 2019 study published in the journal Nanotoxicology, researchers recreated the first phase of digestion in mice and fed them titanium dioxide, then examined whether accumulation occurred in the organs. Researchers wrote: “Significant accumulation of titanium was observed in the liver and intestine of E171-fed mice; in the latter a threefold increase in the number of TiO2 particles was also measured. Titanium accumulation in the liver was associated with necroinflammatory foci containing tissue monocytes/macrophages. Three days after the last dose, increased superoxide production and inflammation were observed in the stomach and intestine. Overall, [this] indicates that the risk for human health associated with dietary exposure to E171 needs to be carefully considered.”

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In conclusion, the use of food-safe titanium dioxide in manufacturing poses both promises and perils. While it is an effective and affordable whitening agent, there are concerns regarding its potential health risks when consumed in large quantities over a long period of time. To address these concerns, it is important for manufacturers to take steps to ensure the safe use of TiO2 in their products, and for regulatory agencies to establish stronger guidelines and regulations regarding its use.

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In conclusion, the titanium dioxide industry faces numerous challenges in terms of pricing strategies and supplier selection. To succeed in this highly competitive market, suppliers must stay informed about market trends, diversify their product offerings, establish strong relationships with key players, explore new distribution models, and prioritize sustainability practices. By doing so, they can maintain profitability while meeting the evolving needs of their customers.

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