Of the products that include the additive in their labels, Thea Bourianne, senior manager at data consultant Label Insights, told Food Navigator USA in May 2021 that more than 11,000 products in the company's database of U.S. food and beverage products listed titanium dioxide as an ingredient. Non-chocolate candy led those numbers at 32%. Cupcakes and snack cakes made up 14%, followed by cookies at 8%, coated pretzels and trail mix at 7%, baking decorations at 6%, gum and mints at 4% and ice cream at 2%.

Lithopone is an inorganic white pigment, obtained from co-precipitation of Zinc sulfide (ZnS) and Barium sulfate (BaSO4). Titanium Dioxide (TiO2) has replaced Lithopone as a white pigment in majority applications as TiO2 is more durable. However, it is much cheaper than TiO2 and has advantages such as low binder requirement and good dispensability. As a white pigment, it can improve the substrate's weather resistance, and improve the fungicidal properties of paint formulations. Some of the major applications of Lithopone include manufacturing of paint pigments, plastic & rubber products, paper, printing inks, cosmetics, and leather & linoleum products. It is commercially available under names such as pigment white 5, Barium zinc sulfate sulfide, Becton White, C.I. 77115, Charlton White, Enamel White, and Zincolith. On the basis of content of ZnS, Lithopone is available at 28%-30% Lithopone and 60% Lithopone.

The natural barite containing more than 95% of barium sulfate is mixed with anthracite in a ratio of 3:1 (mass), and is pulverized to a diameter of about 2 cm or less to enter a reduction furnace, and the front stage of the furnace temperature is controlled by 1000 to 1200 ° C, and the latter stage is 500 to 600 ° C, the reduction furnace rotates at a speed of 80s per revolution, the reaction conversion rate is 80% to 90%, the obtained barium sulfide enters the leaching device, the control temperature is above 65 ° C, and the content of barium sulfide is 701%, and then enters the clarification. The barrel is clarified and then added with zinc sulfate to control the zinc sulfate content to be greater than 28%, and the pH is 8-9, and a mixture of barium sulfate and zinc sulfide having a density of