Stability and darkening

We've measured many different immunological markers, both in the mucosa of the intestine and the lymphoid organs part of the intestine and we didn't see any inflammation there or changes in white blood cell number, Kaminski said. They also looked at the spleen where titanium dioxide was taken up into the bloodstream. You would expect [titanium dioxide] would be filtered out in the spleen and maybe induce inflammation there, but we did not see that, Kaminski added.

Moreover, titanium dioxide is also used in rubber formulations to improve the processing and curing properties of rubber compounds. It acts as a catalyst in the vulcanization process, speeding up the cross-linking of rubber molecules and enhancing the overall performance of the final product. This results in rubber products that are stronger, more flexible, and better suited for a wide range of applications.

Cosmetics

In some studies, E171 was given to animals in drinking water without the stabilizers that keep E171 suspended in the liquid. Without stabilizers, E171 can settle and prevent the ingredient from combining with surrounding ingredients.