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In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”

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ba311 suppliers2025-08-16 15:42
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In a 2022 study published in the Journal of Hazardous Materials, scientists wanted to examine the effects of titanium dioxide as a food additive on atherosclerosis in mice. (Atherosclerosis refers to a hardening of the arteries.) Researchers fed mice 40 mg/kg of the food additive every day for 4 months, and found that it not only altered gut microbiota but also led to a significantly increased atherosclerotic lesion area, especially in animals that consumed a high-choline western diet (HCD).

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ba311 suppliers2025-08-16 15:22
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TiO2 is a white pigment that is commonly used in the production of paints, plastics, and paper. It is known for its brightness, opacity, and durability, making it an ideal choice for products that require a high level of whiteness and coverage. TiO2 is also used in sunscreen lotions and cosmetics to provide protection against harmful UV rays. In addition, TiO2 is used in the food industry as a food additive to enhance the appearance of products such as candies and confectionery.


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ba311 suppliers2025-08-16 15:10
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  • Several leading suppliers have established themselves in the global market for food-grade anatase titanium dioxide. One such supplier is Evonik Industries, a German multinational chemical company. They offer high-quality TiO2 products under the brand name Tixosil, specifically designed for food applications. Their products adhere to strict quality standards and comply with global regulations.

  • Resumo–Este artigo discute a descoberta de litopônio fosforescente em desenhos de aquarela do artista americano John La Farge datados de entre 1890 e 1905 e a história do litopônio na indústria de pigmento no final do século XIX e início do século XX. Apesar de ter muitas qualidades desejáveis para o uso em aquarela branca ou tintas a óleo, o desenvolvimento do litopônio como um pigmento de artistas foi prejudicado por sua tendência a se escurecer na luz solar. Sua disponibilidade para e uso por parte de artistas ainda não está clara, uma vez que os catálogos comerciais dos vendedores de tintas geralmente não eram explícitos na descrição de pigmentos brancos como algo que contém litopônio. Além disso, o litopônio pode ser confundido com o branco de chumbo durante o exame visual e sua fosforescência de curta duração pode ser facilmente perdida pelo observador desinformado. O litopônio fosforescente foi documentado em apenas um outro trabalho até hoje: uma aquarela de Van Gogh. Além da história da manufatura do litopônio, o artigo detalha o mecanismo para a sua fosforescência e sua identificação auxiliada pela espectroscopia de Raman e espectrofluorimetria.

  • Global TIO2 manufacturers, such as Cristal, Tronox, and Evonik, are not only competing on product quality but also on their sustainability credentials. They invest heavily in research and development to innovate new production techniques, minimize environmental impact, and cater to the growing demand for 'green' products.