lithopone is manufacturer

A  2023 study published in the journal Environmental Research, scientists examined the effect of titanium dioxide nanoparticles on important gut bacteria in mice. Their results showed “the growth inhibitory effects could be associated with cell membrane damage caused by titanium dioxide nanoparticles to the bacterial strains. Metabolomics analysis showed that TiO2 NPs caused alterations in multiple metabolic pathways of gut bacteria, such as tryptophan and arginine metabolism, which were demonstrated to play crucial roles in regulating gut and host health.” The researchers also found that four different neuroprotective metabolites “were significantly reduced” in urine and in vitro bacteria and vivo urine samples. The researchers concluded: “Increasing evidence implies that the gut microbiome plays a profound role in regulating host metabolism. Our results illustrated that TiO2 NPs hindered the growth of four beneficial gut bacterial strains.”

...

The demand for 30-50nm TiO2 powders stems from their enhanced surface area to volume ratio, which amplifies their reactivity and photocatalytic efficiency. This attribute is paramount in applications such as photovoltaics, where these nanoparticles can boost energy conversion rates in solar cells. In the field of environmental remediation, they serve as potent catalysts for degrading pollutants under light exposure. Furthermore, the exceptional transparency and refractive index of TiO2 nanoparticles make them ideal for high-performance coatings and paints, offering improved durability and aesthetic appeal.

...