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Australian researchers examined how titanium dioxide as a food additive affected gut microbiota in mice by orally administering it in drinking water. The study, published in the journal Frontiers in Nutrition in 2019, found the treatment could “alter the release of bacterial metabolites in vivo and affect the spatial distribution of commensal bacteria in vitro by promoting biofilm formation. We also found reduced expression of the colonic mucin 2 gene, a key component of the intestinal mucus layer, and increased expression of the beta defensin gene, indicating that titanium dioxide significantly impacts gut homeostasis.” The changes were then linked to colonic inflammation, along with a higher expression of inflammatory cytokines, which are signal proteins that help with regulation. The researchers concluded that titanium dioxide “impairs gut homeostasis which may in turn prime the host for disease development.”

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In conclusion, the cost of titanium dioxide from suppliers is determined by a variety of factors, including raw material availability, market demand, economic conditions, competition, and production processes. Suppliers work hard to balance these factors in order to provide a high-quality product at a competitive price. By understanding the complexities of the titanium dioxide market, customers can make informed decisions when purchasing products that contain this essential pigment.

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Wegman’s puts titanium dioxide in its Original Macaroni and Cheese. Campbell’s Healthy Request Chunky Chicken Corn Chowder has it, as does Food Club’s Chunky New England Clam Chowder. Marzetti uses the color agent to brighten its Cream Cheese Fruit Dip. Dairy products usually don’t need titanium dioxide to look white, but Kroger has decided to add titanium dioxide to its Fat Free Half-and-Half. And titanium dioxide isn’t only in especially white or brightly colored foods: Little Debbie adds it to Fudge Rounds and many other products. According to the Food Scores database maintained by Environmental Working Group, more than 1,800 brand-name food products have titanium dioxide on their ingredients list. That said, it can still lurk as an unspecified “artificial color,” or labels might simply say “color added.”

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  • The International Agency for Research on Cancer (IARC) has listed titanium dioxide as a Group 2B carcinogen — an agent that may be carcinogenic but lacks sufficient animal and human research. This has caused concern for its safety in food products (1112).

  • Calcium carbonate, a versatile chemical compound, is a fundamental ingredient in various industries, from construction to pharmaceuticals. Its production typically takes place in specialized factories, known as calcium carbonate factories, which can be classified based on their production methods and end products. This article delves into the classification of these factories, providing an understanding of their operational dynamics.
  • Titanium dioxide is a widely used white pigment in various applications such as paint, coatings, plastics, paper, and even food products. It is known for its brightness and high refractive index, making it the preferred choice for imparting opacity and whiteness in many products.