tr 52 titanium dioxide
Recently, Yanagisawa et al. reported that the transdermal exposure (mimicking skin-barrier dysfunction or defect) of NC/Nga mice to TiO2 NPs (15, 50, or 100 nm), in combination with allergen, aggravated atopic dermatitis-like lesions through a T-helper type 2 (Th2) dominant immune response. The study also indicated that TiO2 NPs can play a role in the initiation and/or progression of skin diseases, since histamine was released, even in the absence of allergen.
The production process of titanium dioxide involves several stages, starting with the extraction of raw materials from mineral ores such as ilmenite, rutile, and anatase. These ores are then processed through various methods, including the sulfate and chloride processes, to produce high-purity titanium dioxide powder. The sulfate process involves treating the ore with sulfuric acid to extract titanium dioxide, while the chloride process uses chlorine gas to produce a purer form of the pigment.
