In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”

Looking ahead to 2023, titanium dioxide will play a key role in various industries. The growth potential of this chemical is huge, and companies like Hebei Caiqing Material Technology Co., Ltd. are well positioned to meet the changing demands of the market. With its individual customization services and dedication to research and development, the company is well-positioned to meet the growing demand and contribute to the advancement of titanium dioxide applications worldwide. Whether in coatings or plastics, titanium dioxide brings innovation, protection and improved product performance to a wide range of customers around the world.