use of titanium dioxide in medicine factories

In addition to supplier evaluation and negotiation, BA311 also covers other critical aspects of supplier management, such as risk management, performance monitoring, and continuous improvement. The guide provides practical guidance on how to identify and mitigate potential risks associated with supplier relationships, how to measure supplier performance over time, and how to engage suppliers in continuous improvement efforts.

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In 2021, the European Food Safety Authority concluded that titanium dioxide is no longer safe in foods due to the same concerns over nanoparticles. As a result, titanium dioxide is now banned as a food additive in the EU. Although studies have shown that the absorption of ingested titanium dioxide is low, evidence suggests that titanium dioxide nanoparticles can accumulate in the body over time. Health Canada deemed it safe in 2022 but noted concerns. Unlike their European counterparts, Canadian officials did not consider studies performed with titanium dioxide nanoparticles alone. 

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