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In conclusion, titanium dioxide is more than just a color additive in nitrile glove production. It significantly boosts the gloves' functionality, durability, and user experience. As the demand for high-quality, reliable personal protective equipment continues to rise, the role of titanium dioxide in nitrile glove factories becomes even more pivotal. Its integration into the manufacturing process underscores the commitment to safety, performance, and innovation that defines the modern era of nitrile glove production.

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In order to contribute with experimental evidence that could help to achieve a better understanding of the field for future regulation, in the present work, the biocompatibility of commercial P25TiO2NPs (one type of TiO2NPs used in sunscreen formulations) and two novel functionalized P25TiO2NPs were evaluated under solar simulated irradiation. White light, generated by red, blue, and yellow LEDs, together with UV ones, was chosen to simulate the solar spectra. Functionalization of TiO2NPs was made with antioxidant vitamins in order to prevent the expected photo-initiated ROS production when nanoparticles are exposed to the simulated solar spectra. Vitamin B2 (riboflavin) and vitamin C were chosen to carry out the functionalization because they are water-soluble, low-cost, and are a constitutive part of biological processes. In addition, it is known that both have the potential to prevent macromolecular oxidation by ROS [23][24][25][26].

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