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In conclusion, industrial grade titanium dioxide is a versatile and essential substance that is used in a wide range of industries. As one of the leading manufacturers of titanium dioxide, we are committed to producing high-quality products that meet the needs of our customers and provide exceptional performance in their applications. With our advanced manufacturing processes, sustainable practices, and dedication to customer service, we are proud to be a trusted partner for manufacturers around the world.

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TiO2 NPs appeared to be more toxic to nematode Caenorhabditis elegans than submicron-sized TiO2.  At a concentration of 1 mg/l, 7 nm particles affected its fertility and survival rate and were more toxic than 20 nm anatase particles. Similarly, Hu et al. showed that rutile particles (10–20 nm), at concentrations above 1 g/kg soil, can be bio-accumulated in earthworms, where they induce oxidative stress, inhibit the activity of cellulase and induce DNA and mitochondrial damage.

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For research published in Archives of Toxicology in 2020, scientists fed one group of mice a solution containing titanium dioxide for one month, and compared it to those that did not receive the additive. They found “the richness and evenness of gut microbiota were remarkably decreased and the gut microbial community compositions were significantly changed” in the titanium dioxide group when compared with the control group. The tests also revealed that the titanium dioxide exposure could cause locomotor dysfunction, or mobility issues “by elevating the excitement of enteric neurons, which might spread to the brain via gut-brain communication by vagal pathway.” The researchers concluded: “These findings provide valuable insights into the novel mechanism of TiO2NP-induced neurotoxicity. Understanding the microbiota-gut-brain axis will provide the foundation for potential therapeutic or prevention approaches against TiO2NP-induced gut and brain-related disorders.”

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{随机栏目} 2025-08-14 19:58 2031