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In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.” 

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In conclusion, titanium dioxide is more than just a color additive in nitrile glove production. It significantly boosts the gloves' functionality, durability, and user experience. As the demand for high-quality, reliable personal protective equipment continues to rise, the role of titanium dioxide in nitrile glove factories becomes even more pivotal. Its integration into the manufacturing process underscores the commitment to safety, performance, and innovation that defines the modern era of nitrile glove production.

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