These processes can significantly reduce the amount of energy and chemicals required, while also generating fewer byproducts These processes can significantly reduce the amount of energy and chemicals required, while also generating fewer byproductsr 5566 titanium dioxide factories.Prof. Matthew Wright, chair of EFSA’s working group on E171, noted: “Although the evidence for general toxic effects was not conclusive, on the basis of the new data and strengthened methods we could not rule out a concern for genotoxicity and consequently we could not establish a safe level for daily intake of the food additive.”