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In 2021, the European Food Safety Authority concluded that titanium dioxide is no longer safe in foods due to the same concerns over nanoparticles. As a result, titanium dioxide is now banned as a food additive in the EU. Although studies have shown that the absorption of ingested titanium dioxide is low, evidence suggests that titanium dioxide nanoparticles can accumulate in the body over time. Health Canada deemed it safe in 2022 but noted concerns. Unlike their European counterparts, Canadian officials did not consider studies performed with titanium dioxide nanoparticles alone. 

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In conclusion, titanium oxide is a valuable and versatile material that is used in a wide range of industries. As a wholesale supplier of titanium oxide, we are proud to provide this essential substance to businesses around the world. Whether you need titanium oxide for paints, ceramics, electronics, or medical applications, we have the expertise and resources to help you find the right product for your needs. Contact us today to learn more about our wholesale titanium oxide products and how we can help your business succeed.

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Looking ahead to 2023, titanium dioxide will play a key role in various industries. The growth potential of this chemical is huge, and companies like Hebei Caiqing Material Technology Co., Ltd. are well positioned to meet the changing demands of the market. With its individual customization services and dedication to research and development, the company is well-positioned to meet the growing demand and contribute to the advancement of titanium dioxide applications worldwide. Whether in coatings or plastics, titanium dioxide brings innovation, protection and improved product performance to a wide range of customers around the world.

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China's dominance in the titanium dioxide market is a testament to its robust industrial infrastructure and advanced chemical processing capabilities. According to industry reports, China accounts for more than half of the global titanium dioxide production, making it the largest producer and exporter of this pigment worldwide. This is largely due to the country's abundant reserves of titanium-bearing minerals, such as ilmenite and rutile, which are the primary raw materials for TiO2 production.

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In a 2017 study published in Scientific Reports, researchers exposed rats to human-relevant levels of E171 to examine the effects of intestinal inflammation and carcinogenesis. They saw that “a 100-day E171 treatment promoted colon microinflammation and initiated preneoplastic lesions while also fostering the growth of aberrant crypt foci in a chemically induced carcinogenesis model.” They continued: “Stimulation of immune cells isolated from Peyer’s Patches [which are clusters of lymphoid follicles found in the intestine] showed a decrease in Thelper (Th)-1 IFN-γ secretion, while splenic Th1/Th17 inflammatory responses sharply increased,” researchers wrote. “A 100-day titanium dioxide treatment promoted colon microinflammation and initiated preneoplastic lesions.” The scientists concluded: “These data should be considered for risk assessments of the susceptibility to Th17-driven autoimmune diseases and to colorectal cancer in humans exposed to TiO2 from dietary sources.”

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