From studies deemed relevant, the experts found that titanium dioxide as a food additive is poorly absorbed by the gastrointestinal tract of mice and rats, with no adverse effects observed in short-term studies in rodents receiving titanium dioxide in their diets. No observed adverse effect levels (NOAELs) of 15,000 milligrams per kilogram of bodyweight (mg/kg BW) per day and 5,000 mg/kg BW per day—the highest doses tested—were established for mice and rats, respectively.

2. Particle Size The application often dictates the required particle size. Suppliers typically offer various grades of barium sulphate, categorized by their particle size distribution. For example, finer particle sizes are often favored in cosmetic applications, while coarser grades may be used in construction materials.

Titanium dioxide is an important chemical compound that is widely used in various applications, including paint, cosmetics, sunscreens, and food coloring. As the demand for this versatile substance continues to grow, the role of titanium dioxide manufacturers becomes crucial in ensuring a stable supply for industries around the world.