lithopone for plastic manufacturers

Mexican researchers sought to evaluate the effects of E171 across a span of conditions in mice, including its influence on behavior, along with the effects on the colon and liver. The research, published in 2020 in the journal Food and Chemical Toxicology, showed that E171 promoted anxiety and induced adenomas, or noncancerous tumors, in the colon. They also found that E171 heightened goblet cells hypertrophy and hyperplasia, which is typically seen in asthma patients and triggered by smoking or external pollutants and toxins. They also noted mucins overexpression in the mice, which can be linked to cancer cell formation. 

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The manufacturing process of lithopone involves several steps, including sulfide precipitation, grinding, classification, and packaging. During the sulfide precipitation stage, zinc sulfide and barium sulfate are reacted in an aqueous solution under controlled conditions to form a precipitate of lithopone. The precipitate is then washed, dried, and ground to the desired particle size distribution. Finally, the ground pigment is classified to remove any oversized or undersized particles and packaged for storage and transportation.

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