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Although barium sulfate is almost completely inert, zinc sulfide degrades upon exposure to UV light, leading to darkening of the pigment. The severity of this UV reaction is dependent on a combination of two factors; how much zinc sulfide makes up the pigments formulation, and its total accumulated UV exposure. Depending on these factors Lithopone B301, Lithopone B311 powder itself may vary in shade over time, ranging from pure white all the way to grey or even black. To suppress this effect, a dopant might be used, like small amount of cobalt salts, which would be added to the formulation. This process creates cobalt-doped zinc sulfide. The cobalt salts help to stabilize zinc sulfide so it will not have as severe a reaction to UV exposure.

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One significant advantage of TiO2 in coatings is its ability to scatter light effectively, which enhances the hiding power and gloss of the paint. It allows for better coverage, reducing the amount of coating needed and ultimately saving costs. Moreover, TiO2's photocatalytic properties can break down organic pollutants under sunlight, making it environmentally friendly and contributing to cleaner air Moreover, TiO2's photocatalytic properties can break down organic pollutants under sunlight, making it environmentally friendly and contributing to cleaner air Moreover, TiO2's photocatalytic properties can break down organic pollutants under sunlight, making it environmentally friendly and contributing to cleaner air Moreover, TiO2's photocatalytic properties can break down organic pollutants under sunlight, making it environmentally friendly and contributing to cleaner airtitanium dioxide in coatings factory.

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Mexican researchers sought to evaluate the effects of E171 across a span of conditions in mice, including its influence on behavior, along with the effects on the colon and liver. The research, published in 2020 in the journal Food and Chemical Toxicology, showed that E171 promoted anxiety and induced adenomas, or noncancerous tumors, in the colon. They also found that E171 heightened goblet cells hypertrophy and hyperplasia, which is typically seen in asthma patients and triggered by smoking or external pollutants and toxins. They also noted mucins overexpression in the mice, which can be linked to cancer cell formation. 

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