tio2 anatase rutile

Hitox and Tio2 are two terms that could potentially refer to brand names or specific types of titanium dioxide products within the industry. While Hitox does not directly correspond to a well-known manufacturer or product line in the TiO2 sector, Tio2 might be seen as an abbreviated form of titanium dioxide. However, it's crucial to note that there are numerous manufacturers of titanium dioxide worldwide, each offering different grades and specialized forms of TiO2 tailored to meet diverse industrial needs.

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The manufacturing process of titanium dioxide typically involves mining ilmenite, rutile, or anatase from natural sources, followed by conversion into TiO2 through various chemical processes. The resulting TiO2 can then be further processed to achieve different particle sizes and coatings that optimize its performance in specific applications. For instance, TiO2 used in sunscreens is often coated to enhance its effectiveness in blocking UV rays without causing skin irritation.

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In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.” 

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