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The gastrointestinal tract is a complex barrier/exchange system, and is the most important route by which macromolecules can enter the body. The main absorption takes place through villi and microvilli of the epithelium of the small and large intestines, which have an overall surface of about 200 m2. Already in 1922, it was recognized by Kumagai, that particles can translocate from the lumen of the intestinal tract via aggregation of intestinal lymphatic tissue (Peyer’s patch, containing M-cells (phagocytic enterocytes)). Uptake can also occur via the normal intestinal enterocytes. Solid particles, once in the sub-mucosal tissue, are able to enter both the lymphatic and blood circulation.

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The production process in a nano-TiO2 factory begins with the selection of high-purity titanium precursors. Through precise control over reaction conditions, including temperature, pressure, and pH levels, scientists can manipulate the formation of either anatase or rutile phases. Advanced techniques such as hydrothermal synthesis, sol-gel processes, and chemical vapor deposition are employed to achieve the desired nanoscale dimensions and crystalline forms Advanced techniques such as hydrothermal synthesis, sol-gel processes, and chemical vapor deposition are employed to achieve the desired nanoscale dimensions and crystalline forms Advanced techniques such as hydrothermal synthesis, sol-gel processes, and chemical vapor deposition are employed to achieve the desired nanoscale dimensions and crystalline forms Advanced techniques such as hydrothermal synthesis, sol-gel processes, and chemical vapor deposition are employed to achieve the desired nanoscale dimensions and crystalline formsanatase and rutile nano-tio2 factory.

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