tio2 p25 factory

Australian researchers examined how titanium dioxide as a food additive affected gut microbiota in mice by orally administering it in drinking water. The study, published in the journal Frontiers in Nutrition in 2019, found the treatment could “alter the release of bacterial metabolites in vivo and affect the spatial distribution of commensal bacteria in vitro by promoting biofilm formation. We also found reduced expression of the colonic mucin 2 gene, a key component of the intestinal mucus layer, and increased expression of the beta defensin gene, indicating that titanium dioxide significantly impacts gut homeostasis.” The changes were then linked to colonic inflammation, along with a higher expression of inflammatory cytokines, which are signal proteins that help with regulation. The researchers concluded that titanium dioxide “impairs gut homeostasis which may in turn prime the host for disease development.”

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In conclusion, titanium dioxide is a versatile and widely used ingredient in the cosmetics industry. Its benefits include broad-spectrum sun protection, natural pigmentation, chemical stability, and non-irritating properties. While there are some safety concerns regarding its use, regulatory agencies have established guidelines to ensure its safe use in cosmetic products. As the demand for natural and safe cosmetic products continues to grow, the future outlook for TiO2 in the cosmetics industry looks promising.

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